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SIRIUS is setting new standards in molecular identification, enabling the elucidation of previously uncharted compounds, and making a valuable contribution to both science and industry. Here you’ll find a variety of posts showcasing how SIRIUS advances metabolomics and molecular identification.

  • Discoveries: Explore how research groups are leveraging the power of SIRIUS to elevate their metabolomics data analysis across various fields, including drug discovery, diagnostics, food industry, environmental toxicology, and materials science. For an extensive list of discoveries, click here.
  • Application Notes: Learn practical strategies from our real-world applications alongside detailed information on how to get the most out of SIRIUS in your analyses.
  • Tutorials: Read our step-by-step guides to help you master SIRIUS features and workflows.
  • Projects: Our commitment is to continue improving SIRIUS and shaping the future of metabolomics research by initiating new research projects.
  • Background: Learn more about the science and concepts behind SIRIUS to get a deeper understanding of its capabilities.
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Discoveries

A liverwort under stress: compound classification with CANOPUS to detect metabolic shifts

Liverworts are chemically diverse plants with unique cell organelles responsible for the synthesis and storage of specialized metabolites. Untargeted metabolomics was used to analyze the metabolic stress response of liverworts without isolating individual metabolites. CANOPUS classified the affected compounds, and helped to map the biochemical pathways of the unique stress response of liverworts compared to vascular plants.

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Franziska Hufsky 2023-03-31 No Comments
Discoveries

Scouring the oceans: Revealing the chemical potential of marine microorganisms with SIRIUS

Marine microorganisms offer a rich source of bioactive compounds with unique structures and remarkable biological activity. This makes them an important resource for the search for new therapeutic compounds, which is one of the most pressing challenges of our time. To narrow down the search to the most promising microorganisms, SIRIUS is nearly doubling the number of natural products annotated to estimate the chemical potential of microbial extracts.

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Franziska Hufsky 2023-03-23 No Comments