Here is a list of discoveries made by independent research groups using the SIRIUS software framework to enhance their metabolomics data analysis.
For more detailed stories, visit our blog.
These findings were neither conducted nor financed by our company. Findings are listed in random order.
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Significant differences in metabolite abundance and composition among microalgae Spirulina, Chlorella, and Amphora.
Hegazi et al. | Sci Rep (2024).
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Annotation of 80% of the previously unknown metabolite features of tall wheatgrass root exudates.
Couvillion et al. | Soil Biology and Biochemistry (2025)
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Biopesticide 6-PP is produced via the polyketide biosynthesis pathway in Trichoderma fungi.
Flatschacher et al. | Microb Cell Fact (2025)
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Upcycling by-products: Coffee waste is a rich source of hydrophilic antioxidants and lipophilic sterols.
Soontontaweesub et al. | Computational and Structural Biotechnology Journal (2025)
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DX protein enhances expression of specialized metabolic pathways in the Streptomyces genomes and might lead to the discovery of novel bioactive molecules.
Apel et al. | Front Cell Dev Biol (2023)
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155 new brown carbon chromophores identified in aqueous-phase reactions of α-dicarbonyls with ammonium or amines.
Yang et al. | Environ Sci Technol (2023)
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Method to reveal the chemical potential of marine microorganisms based on microbial extracts.
Loarer et al. | Microorganisms (2023)
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Metabolome composition of mature and immature seeds from different cereal and leguminous plants.
Saied et al. | Food Chem (2023)
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Strong interdependence and metabolic rewiring of the algal partner in radiolaria photosymbiosis, where the host extensively transforms algal metabolites and the algal cell membrane is significantly rearranged.
Nikitashina et al. | ISME J (2025)
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Kakadu plum extracts shows antiproliferative effects against MCF7 breast adenocarcinoma cells.
Dissanayake et al. | Food Bioscience (2023)
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Zinc anodes, used to protect against corrosion in marine environments, affect the metabolism of oysters.
Imbert-Auvray et al. | Metabolites (2023)
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Plants tailor their defenses based on the presence of herbivores rather than herbivore identity.
Mezzomo et al. | Ecol Evol (2023)
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Understanding the dynamics of thawing permafrost and its impact on climate change is essential for developing strategies to cope with its effects.
McGivern et al. | Nat Microbiol (2024)
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Lipophilic diterpenoids and retinoids in seaweed reduce rumen methane production by 30% while shifting fermentation patterns.
Curtasu et al. | Algal Research (2025)
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Homologous series of previously overlooked polymerization byproducts detected near fluoropolymer production plant.
Dalmijn et al. | Environ Sci Technol (2025)
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Metabolites from citrus juices improve herbal therapy against paracetamol-induced liver toxicity.
Shalaby et al. | ACS Omega (2023)
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Identification of 100 light-absorbing brown carbon molecules, 33 of which have never been reported before.
Xing et al. | JGR Atmospheres (2023)
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Chemical composition and anti-inflammatory properties of prickly goldenfleece could be a valuable source of bioactive compounds for food and health applications.
Saber et al. | Food Chemistry (2023)
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Phosphorous limitation led to the creation of new types of lipids in Desulfatibacillum alkenivorans as survival strategy.
Ding et al. | PNAs (2024)
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Females of the red-necked wasp moth have higher concentrations of potential defensive compounds than males.
Binns et al. | R Soc Open Sci (2025)
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Multi-omic analysis reveals PHACTR1 as a master regulator of cell cycle, iron metabolism, and mitochondrial bioenergetics in human vascular cells.
Wolhuter et al. | Communications Biology (2026)
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Nutritional components of coconut flesh.
Guo et al. | Metabolites (2023)
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New protocol to identify structurally related impurities in pesticides for assessing their environmental impact and risks.
Li et al. | Microchemical Journal (2023)
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Metabolic adaptations of a salt-tolerant willow are specific to the plant organ and the salt anion.
Sas et al. | Plant J. (2025)
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Decreased concentration of two carotenoids after UV filter explosion might be indicative of an alteration in the photosynthetic capacity of corals.
Clergeaud et al. | Metabolites (2023)
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Ethanol extraction for human faecal metabolomics is a valid, safer, and more economical alternative to the common methanol extraction.
Zuffa et al. | Anal Chem. (2025)
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Unique phytochemical fingerprints of Phragmites australis lineages suggest that metabolomic evenness may be a critical trait within plant species.
Salgado et al. | J Chem Ecol (2023)
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Monophasic extraction with 400 nm beads and 60-minute on-bead protein digestion is the most reproducible, efficient, and cost-effective solution for in-house multiomics (metabolites, lipids, proteins) workflows in HepG2 cells.
Arnst et al. | Analytical and Bioanalytical Chemistry (2025)
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Identification of fenozan in wastewater as a key biomarker for human exposure to synthetic phenolic antioxidants.
Meyer et al. | Environ Int. (2025)
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Honey ia a bio-indicator for flame retardants in air.
Leung et al | Chemosphere (2023)
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Mycobacteria use the MelH protein to neutralize toxic lipids, allowing them to survive in the host.
Chakraborti et al. | ACS Omega. (2025)
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Decoding the crucial role of the gut microbiome in altering the chemical structure and efficacy of GPCR drugs.
Wu. et al. | Nat Chem (2025)
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Highly halogenated compounds are potential contributors to the high antibacterial activity in tetrasporophyte stage of red alga Asparagopsis armata.
Parchemin et al. | Marine Drugs (2023)
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Selective cytotoxic activity of dinoflagellate Amphidinium eilatiense extracts against cancer cells is linked to a rich chemical diversity.
Osorio-Ramírez et al. | Toxins (2025)
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Novel method to study ozonation in water treatment plants to remove cyanobacterial toxins from drinking water.
Rougé et al. | Environ Sci Technol (2024)
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Microbial biocontrol agents lead to major metabolic re-programming in fungi
Fernando Devasahayam et al. | J Plant Dis Prot (2024)
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Rust infection in common beans enriched metabolomic pathways, biosynthesis of secondary metabolites, protein processing in the endoplasmic reticulum, and purine metabolism among others.
Makhumbila et al. | BMC Plant Biol (2025)
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New chlorophylls in coastal halophyte plant that exhibit potent, selective toxicity against colorectal cancer cells.
Gu et al. | RSC Adv (2025)
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The International Space Station has a unique and extreme microbial and chemical environment with distinct signatures within each module.
Salido et al. | Cell (2025)
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Untargeted 2D chromtography MS/MS approach unravels the complex structures of depolymerized lignin to turn it into valuable biomaterials.
Tammekiviet al. | Anal Chim Acta (2024)
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33 emerging contaminants identified in global tap water — 25 for the first time.
Muñiz-Bustamante et al. | Environmental Pollution (2026)
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FODMAPs are influencing health-positive metabolites in plasma of irritable bowel syndrome patients.
Nordin et al. | Am J Physiol Regul Integr Comp Physiol (2023)
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Ash trees resistant to ash dieback could also help protect against emerald ash borer infestations.
Gossner et al. | New Phytologist (2023)
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Different paths to chemical diversity in highland and lowland willow species.
Volf et al. | Ecology Letters (2023)
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Ketamine distribution in the brain improves understanding on how ketamine traverses the blood-brain barrier.
Vallianatou et al. | ACS Chem Neurosci (2024)
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Anti-viral compounds in Caesalpinia mimosoides help to inhibit influenza by targeting two critical viral proteins.
Klamrak et al. | Sci Rep (2025)
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The methanogenic archaeon Methanosarcina barkeri can reduce naturally occurring iron oxides in aquatic sediments' methanogenic zones.
Eliani-Russak et al. | Front Microbiol (2023)
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Neuroprotective effects of secondary metabolites in mulberry plant extracts on Alzheimer’s Disease.
Hegazi et al | Food Funct (2014)
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New degradation metabolites and potential metabolic pathway of novel designer drug O-PCE identified.
Magny et al. | J Pharm Biomed Anal (2024)
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18 novel hop-acid analogues identified in brewery waste revealing its high antioxidant potential.
Scognamiglio et al. | Food Chemistry (2026)
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Highly specific "Gold" markers in 14 yellow dye plants enable the precise botanical authentication of ancient textiles.
Mas-Normand et al. | Microchemical Journal (2025)
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32-44% of polar chemicals in offshore oil discharges are persistent, in particular N-substituted aromatic ring structures.
Møller et al. | Environ Sci Technol (2025)
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Nitrogen source drives Microcystis (a primary driver of harmful freshwater algal blooms) exometabolome composition more than strain, with nitrate fueling peak chemical diversity.
Peck et al. | Environ Microbiol Rep. (2025)
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Innovative approach to prioritise chemical profiling over exhaustive identification for analysing and comparing biomes.
Peets et al. | bioRxiv (2025)
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Green solvents can effectively extract diverse bioactive compounds from lemon balm leaves.
Spaggiari et al. | Advances in Sample Preparation (2025)
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New ecdysteroids with potential skin aging therapeutic benefits discovered in the Korean plant Ajuga spectabilis.
Park et al. | ACS Omega (2023)
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Increase in released greenhouse gases in Northern peatlands is likely due to changes in metabolic activity rather than microbial community changes.
Duchesneau et al. | Nat Commun (2025)
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Microtiter plate cultivation systems provide a robust platform for discovering novel bacterial natural products by enabling broader access to chemical diversity.
Lindig et al. | Biotechnol Bioeng (2025)
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Terpenoids might contribute to the success of M. calvescens as an invasive species.
Clerissi et al. | Microorganisms (2023)
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Previously undetected chemicals with potential estrogenic activity in drinking water from regions with high breast cancer incidence.
Black et al. | Environ Sci Technol. (2025)
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Major antihypertensive constituents of Kinkéliba decoction confirmed through high-resolution metabolite annotation.
Vuadens et al. | Frontiers in Natural Products (2026)
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Arctic microbes eat fresh plants instead of old soil—keeping ancient carbon safely stored.
Ayala-Ortiz et al. | Front Mol Biosci. (2025)
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Multi-omics reveals coating-specific signatures—like ceramides and glucosinolates—that govern biofilm resilience.
Ferré et al. | Sci Rep (2026)
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In ruminants, rutin is first degraded to quercetin by rumen microbes, which is then biotransformed into various phenolic compounds that ultimately result in 4-methylcatechol-1-sulfate and isorhamnetin-glucuronide sulfate as the main metabolites found in the blood
Aldian et al. | Journal of Animal Scienc (2025)
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Specific metabolites identified as potential selection traits to improve Fusarium resistance in maize.
Cao et al. | Front Plant Sci (2023)
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Annotating nitazine (high-potency synthetic opioid) metabolites and major markers for enhanced detection.
Magny et al. | Metabolites (2025)
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Matrix Method: Streamlined, automated method using barcoded tubes to extract both DNA and metabolites simultaneously from human and environmental samples.
Brennan et al. | Microbiology Spectrum (2025)
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Diurnal carbohydrate and metabolite production in sugarcane and energy-cane reveals differences in growth strategies.
Silva et al. | Industrial Crops and Products (2023)
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SIRIUS compound classification reveals how maternal and environmental factors shape infant gut metabolism.
Kvitne et al. | Cell Host Microbe (2025)
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SIRIUS tentatively identified dadahol A in hemp roots, guiding the discovery of neolignans with cytotoxic activity against pediatric cancer cells.
Brownstein et al. | J Cannabis Res (2025)
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Women with ovarian malignancies had significantly higher urinary levels of endocrine-disrupting chemicals.
Plešnik et al. | Environ Sci Technol (2025)
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Testing different reversed-phase LC columns and mobile phase modifiers to improve coverage of intestinal lipids for non-targeted lipidomics.
Selmi et al. | J Chromatogr B Analyt Technol Biomed Life Sci (2024)
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Interplay between dietary patterns, plasma metabolites, and colorectal cancer risk
Bodén et al. | Sci Rep (2024)
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Grapevine root extracts rich in oligostilbenes show high antifungal activity against fungal plant pathogen that affects cereal crops.
Tardif et al. | J. Agric. Food Chem. (2024)
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MCheM chemical labeling provides structural information to constrain the molecular structure search space in SIRIUS and boost annotation accuracy.
Vitale et al. | Nature Communications (2025)
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Tracing thousands of neuroactive metabolites from plant to pill: Vertigoheel retains characteristic constituents from its natural sources in all tested formulations.
Dunkel et al. | International Journal of Molecular Sciences (2026)
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Antioxidant-rich extract from Ceratonia siliqua pods with potential for a biocompatible topical therapy.
De Luca et al. | Antioxidants (2023)
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Microbiome of eelgrass produces broad-spectrum antibiotics with potent activity against waterborne pathogens.
Tasdemir et al. | Sci Total Environ (2024)
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Chemical pollination syndrome: bird-syndrome nectar shows convergence on chemical traits distinct from bee-syndrome nectar.
MacNeill et al. | New Phytologist (2025)
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Detailing the metabolic basis for the production of sesquiterpenoids in the medicinal mushroom Sanghuangporus.
Cho et al. | BMC Genomics (2025)
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Potential to enhance the skin health: changes in the skin metabolome more pronounced than in microbial composition.
Li et al | Front Med (2023)
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Cortisol, sumatriptan, and glutamine are crucial metabolites associated with the treatment of migraines with triptans.
Kogelman et al. | Sci Rep (2023)
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Metabolites identified from A. absinthium extracts support the traditional use for stomach problems.
Boeing et al. | J Ethnopharmacol (2023)
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The microbial diversity and metabolite production of the tropical ascidian Eudistoma vannamei reveals its role as a holobiont rich in secondary metabolites.
Bauermeister et al. | Mar Environ Res (2024)
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Potent antidiabetic compounds in cluster fig (Ficus racemosa) fruit extracts.
Suil et al. | LWT (2025)
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Metabolites altered up to 14 years before diagnosis enable the prediction of Crohn’s disease with high accuracy years before symptoms appear.
Lemser et al. | Clinical Gastroenterology and Hepatology (2026)
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Previously overlooked toxic drivers identified in the air, including 2-indanone and 2-vinylpyridine.
Sunyer-Caldú et al. | Environmental Science & Technology (2026)
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Mycobacteria use the MelH protein to neutralize toxic lipids, allowing them to survive in the host.
Chakraborti et al. | ACS Omega. (2025)
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Potential new UV-protective amino acids identified in Baltic flatfish eyes.
Hammerle et al. | Frontiers in Marine Science (2025)
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SIRIUS as part of a new screening platform to efficiently discover antifungal drugs from natural sources.
Brittin et al. | Molecules (2025)
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White adipose tissue plays a crucial role in regulating metabolism throughout the hibernation cycle.
Heinis et al. | Front Physiol (2023)
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Cell surface glycans and membrane lipids are influential drivers of adaptation to heat stress in rice coral hosting thermosensitive and thermotolerant symbionts.
Tortorelli et al. | ISME J (2025)
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Deep-sea black yeasts adapt to extreme salinity by remodeling membranes and accumulating plant-like amino acids and novel aminocyclitols to maintain osmotic balance.
Camacho-López et al. | Communications Biology (2026)
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Link between microbial community structure and chemical profile of the surface metabolome in Saccharina latissima.
Adouane et al. | FEMS Microbiology Ecology (2025)
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Novel urinary biomarkers to distinguish giant panda pregnancy from pseudopregnancy as early as the first weeks of embryonic development.
Cools et al. | Scientific Reports (2025)
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48 antioxidation active metabolites identified in Ginger.
Wang et al. | Food Chem (2023)
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Biochemical pathways and compounds of the unique stress response of liverworts with potential cytotoxicity against human cancer cell lines.
Blatt-Janmaat et al. | Metabolomics (2023)
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Non-targeted approach uncovers plastic-related contaminants in liquor products, including three unanticipated compounds.
He et al. | Food Control (2024)
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Microbial decomposition of human cadavers as data basis for a forensic tool to predict time since death.
Burcham et al. | Nat Microbiol (2024)
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Metabolite linked to dual-species biofilm pathogenesis in cystic fibrosis identified.
Uzi-Gavrilov et al. | Angewandte Chemie International Edition (2023)
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Potentially allergenic transformation products of tattoo pigments identified in new online-LC-EC-MS approach.
Wolf et al. | Anal Bioanal Chem (2025)
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Endophytic bacteria aid in controlling fusarium wilt disease and enhancing tomato plant growth through bioactive secondary metabolites.
Sriwati et al. | Physiological and Molecular Plant Pathology (2023)
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Metabolomic profiles of three Ficus species to investigate phytochemistry, chemotaxonomy and potential medical use.
Bakry et al. | Journal of Pharmaceutical and Biomedical Analysis (2023)
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Eccrine finger sweat analysis reveals healthy lifestyle shifts in children with overweight after long-term nutritional education and lifestyle intervention.
Wolf et al. | iScience (2025)
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Glacial rivers deliver highly bioavailable aliphatic matter to Arctic fjords, which is rapidly transformed or diluted as it enters the marine carbon cycle.
Mostovaya et al. | Journal of Geophysical Research: Biogeosciences (2025)
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Robust biomarker candidate identified for standardizing exhaled breath sample collection.
Schaar et al. | Analytica Chimica Acta (2025)
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Unstable metabolites in neonatal dried blood spot should be carefully monitored in long-term storage.
Ottosson et al. | J Am Soc Mass Spectrom (2023)
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Multidimensional optimization of cell morphology increases the reproducibility of microbial metabolic footprints by 50% across different cultivation systems.
Lindig et al. | Scientific Reports (2026)
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Brazilian iron-cave bacteria produce rare cyclopeptides with significant cytotoxic activity against cancer cells.
Kato et al. | Chemistry & Biodiversity (2026)
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The antimicrobial agent trimethoprim influences chemical interactions between cystic fibrosis pathogens affecting virulence factors.
Jin et al. | CS Chem Biol (2025)
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Biotransformation of levofloxacin in wastewater by basidiomycete fungal strains leads to decreased antibiotic activity.
Ayed et al. | Ecotoxicology and Environmental Safety (2024)
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Drug metabolites and drugrelated impurities in human plasma identified without reference standards and a priori knowledge of first- and second-pass drug metabolism.
Singh et al. | Exposome (2026)
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Metabolomics study of black apples revealed the chemical diversity of fungus-produced secondary metabolites in black apple microbiomes.
Cowled et al. | Appl Environ Microbiol (2024)
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Metabolites in maize grown on sustainable push-pull fields that enhance its natural defense against pests.
Lang et al. | ACS Agric Sci Technol (2024)
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Defense syndromes in willows result from a complex interplay of selection pressures and trade-offs.
Leong et al. | Oecologia (2024)
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Hybrid diversity in Baccharis is driven by secondary metabolites, while primary metabolism remains conserved.
Zafra-Delgado et al. | Plant J. (2025)
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Metabolite from actinobacteria strain from Egyptian soil is a promising candidate as a multidrug efflux pump inhibitor.
Hamed et al. | Metabolites (2023)
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Stable isotope labeling serves as a detection strategy to distinguish biologically relevant features from background signals.
Favilli et al. | Anal Bioanal Chem (2023)
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Environmental fate of formulation ingredients in commercial pesticides.
Ghosson et al. | Journal of Mass Spectrometry (2023)
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Marine prokaryotes hold vast potential for discovering new drug candidates.
Wei et al. | Microbiome (2023)
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Blechnic acid B: novel lignan discovered in ferns of the Blechnaceae family.
Ufland et al. | Plant Biology (2025)
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Plant extracts as reducing agents for the environmentally friendly synthesis of silver nanoparticles.
Salgado et al. | Surfaces and Interfaces (2023)
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Accelerated photoaging and contact with water significantly increase the degradation and transformation rates of rubber-derived chemicals.
McMinn et al. | Environmental Science & Technology (2026)
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False daisies contain anti-inflammatory, antioxidant and anti-collagenase ingredients with anti-aging potential .
Le Cabec et al. | S. Afr J Bot (2023)
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Key chemical cues for designing a biomaterial that mimics the chemical landscape of healthy reefs to enhance coral settlement.
Kundu et al. | Trends Biotechnol (2025)
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Oscillibacter species in the gut microbiome may help lower cholesterol levels, potentially benefiting heart health.
Li et al. | Cell (2024)
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Metabolites of Aspergillus niveus are promising leads for developing new potent cholinesterase inhibitors against Alzheimer's disease.
Hamed et al. | Molecules (2023)
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Common and previously unreported parabens and plastic-related contaminants identified in human milk.
Chi et al. | Chemosphere 2025
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Identify and link microbial metabolites to their producers with microbeMASST and SIRIUS.
Zuffa et al. | Nat Microbiol (2024)
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Molecular explanation for the longer time needed to establish the low-compatibility interaction between the ectomycorrhizal fungus Tricholoma vaccinum and pine.
Ezediokpu et al. | Front Microbiol (2023)
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Extremophilic fungi dissolve Martian-like hematite using a cocktail of siderophores and organic acids, creating stable chemical biosignatures detectable by future planetary missions.
dos Santos et al. | JACS Au (2026)
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Domesticated common bean varieties exhibit reduced metabolic diversity and specialization compared to their wild counterparts.
de Souza et al. | Plant J (2023)
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Climate and island residence time influence plant specialised chemical diversity.
Moreira et al. | Global Ecology and Biogeography (2025)
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37 unique secondary metabolites identified in the metabolome of the invasive Guinea grass.
Morrison et al. | Ecosphere (2023)
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Homologous series of previously overlooked polymerization byproducts detected near fluoropolymer production plant.
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Upcycling by-products: Coffee waste is a rich source of hydrophilic antioxidants and lipophilic sterols.
Loading...new -
Metabolites from citrus juices improve herbal therapy against paracetamol-induced liver toxicity.
Loading... -
Microbial biocontrol agents lead to major metabolic re-programming in fungi
Loading... -
Metabolome composition of mature and immature seeds from different cereal and leguminous plants.
Loading... -
The antimicrobial agent trimethoprim influences chemical interactions between cystic fibrosis pathogens affecting virulence factors.
Loading... -
New ecdysteroids with potential skin aging therapeutic benefits discovered in the Korean plant Ajuga spectabilis.
Loading... -
Molecular explanation for the longer time needed to establish the low-compatibility interaction between the ectomycorrhizal fungus Tricholoma vaccinum and pine.
Loading... -
Blechnic acid B: novel lignan discovered in ferns of the Blechnaceae family.
Loading...new -
Microtiter plate cultivation systems provide a robust platform for discovering novel bacterial natural products by enabling broader access to chemical diversity.
Loading... -
Endophytic bacteria aid in controlling fusarium wilt disease and enhancing tomato plant growth through bioactive secondary metabolites.
Loading... -
Deep-sea black yeasts adapt to extreme salinity by remodeling membranes and accumulating plant-like amino acids and novel aminocyclitols to maintain osmotic balance.
Loading...new -
Grapevine root extracts rich in oligostilbenes show high antifungal activity against fungal plant pathogen that affects cereal crops.
Loading... -
Highly specific "Gold" markers in 14 yellow dye plants enable the precise botanical authentication of ancient textiles.
Loading...new -
Metabolomic profiles of three Ficus species to investigate phytochemistry, chemotaxonomy and potential medical use.
Loading... -
FODMAPs are influencing health-positive metabolites in plasma of irritable bowel syndrome patients.
Loading... -
Biotransformation of levofloxacin in wastewater by basidiomycete fungal strains leads to decreased antibiotic activity.
Loading... -
Drug metabolites and drugrelated impurities in human plasma identified without reference standards and a priori knowledge of first- and second-pass drug metabolism.
Loading...new -
Lipophilic diterpenoids and retinoids in seaweed reduce rumen methane production by 30% while shifting fermentation patterns.
Loading...new -
Metabolite from actinobacteria strain from Egyptian soil is a promising candidate as a multidrug efflux pump inhibitor.
Loading... -
The International Space Station has a unique and extreme microbial and chemical environment with distinct signatures within each module.
Loading... -
Oscillibacter species in the gut microbiome may help lower cholesterol levels, potentially benefiting heart health.
Loading... -
Novel method to study ozonation in water treatment plants to remove cyanobacterial toxins from drinking water.
Loading... -
Identification of fenozan in wastewater as a key biomarker for human exposure to synthetic phenolic antioxidants.
Loading...new -
Biochemical pathways and compounds of the unique stress response of liverworts with potential cytotoxicity against human cancer cell lines.
Loading... -
Nutritional components of coconut flesh.
Loading... -
Climate and island residence time influence plant specialised chemical diversity.
Loading...new -
Robust biomarker candidate identified for standardizing exhaled breath sample collection.
Loading...new -
Monophasic extraction with 400 nm beads and 60-minute on-bead protein digestion is the most reproducible, efficient, and cost-effective solution for in-house multiomics (metabolites, lipids, proteins) workflows in HepG2 cells.
Loading...new -
Brazilian iron-cave bacteria produce rare cyclopeptides with significant cytotoxic activity against cancer cells.
Loading...new -
Zinc anodes, used to protect against corrosion in marine environments, affect the metabolism of oysters.
Loading... -
Cortisol, sumatriptan, and glutamine are crucial metabolites associated with the treatment of migraines with triptans.
Loading... -
SIRIUS tentatively identified dadahol A in hemp roots, guiding the discovery of neolignans with cytotoxic activity against pediatric cancer cells.
Loading...new -
Chemical composition and anti-inflammatory properties of prickly goldenfleece could be a valuable source of bioactive compounds for food and health applications.
Loading... -
Mycobacteria use the MelH protein to neutralize toxic lipids, allowing them to survive in the host.
Loading...new -
Increase in released greenhouse gases in Northern peatlands is likely due to changes in metabolic activity rather than microbial community changes.
Loading...new -
Multidimensional optimization of cell morphology increases the reproducibility of microbial metabolic footprints by 50% across different cultivation systems.
Loading...new -
Plant extracts as reducing agents for the environmentally friendly synthesis of silver nanoparticles.
Loading... -
Strong interdependence and metabolic rewiring of the algal partner in radiolaria photosymbiosis, where the host extensively transforms algal metabolites and the algal cell membrane is significantly rearranged.
Loading... -
Rust infection in common beans enriched metabolomic pathways, biosynthesis of secondary metabolites, protein processing in the endoplasmic reticulum, and purine metabolism among others.
Loading... -
Women with ovarian malignancies had significantly higher urinary levels of endocrine-disrupting chemicals.
Loading... -
Significant differences in metabolite abundance and composition among microalgae Spirulina, Chlorella, and Amphora.
Loading... -
Annotating nitazine (high-potency synthetic opioid) metabolites and major markers for enhanced detection.
Loading... -
Major antihypertensive constituents of Kinkéliba decoction confirmed through high-resolution metabolite annotation.
Loading...new -
Specific metabolites identified as potential selection traits to improve Fusarium resistance in maize.
Loading... -
White adipose tissue plays a crucial role in regulating metabolism throughout the hibernation cycle.
Loading... -
Potentially allergenic transformation products of tattoo pigments identified in new online-LC-EC-MS approach.
Loading... -
Common and previously unreported parabens and plastic-related contaminants identified in human milk.
Loading... -
In ruminants, rutin is first degraded to quercetin by rumen microbes, which is then biotransformed into various phenolic compounds that ultimately result in 4-methylcatechol-1-sulfate and isorhamnetin-glucuronide sulfate as the main metabolites found in the blood
Loading... -
Multi-omics reveals coating-specific signatures—like ceramides and glucosinolates—that govern biofilm resilience.
Loading...new -
Link between microbial community structure and chemical profile of the surface metabolome in Saccharina latissima.
Loading... -
Identify and link microbial metabolites to their producers with microbeMASST and SIRIUS.
Loading... -
Metabolites of Aspergillus niveus are promising leads for developing new potent cholinesterase inhibitors against Alzheimer's disease.
Loading... -
Marine prokaryotes hold vast potential for discovering new drug candidates.
Loading... -
Non-targeted approach uncovers plastic-related contaminants in liquor products, including three unanticipated compounds.
Loading... -
Different paths to chemical diversity in highland and lowland willow species.
Loading... -
48 antioxidation active metabolites identified in Ginger.
Loading... -
Metabolite linked to dual-species biofilm pathogenesis in cystic fibrosis identified.
Loading... -
Annotation of 80% of the previously unknown metabolite features of tall wheatgrass root exudates.
Loading... -
Mycobacteria use the MelH protein to neutralize toxic lipids, allowing them to survive in the host.
Loading...new -
Previously overlooked toxic drivers identified in the air, including 2-indanone and 2-vinylpyridine.
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Metabolomics study of black apples revealed the chemical diversity of fungus-produced secondary metabolites in black apple microbiomes.
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Novel urinary biomarkers to distinguish giant panda pregnancy from pseudopregnancy as early as the first weeks of embryonic development.
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SIRIUS as part of a new screening platform to efficiently discover antifungal drugs from natural sources.
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Eccrine finger sweat analysis reveals healthy lifestyle shifts in children with overweight after long-term nutritional education and lifestyle intervention.
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Glacial rivers deliver highly bioavailable aliphatic matter to Arctic fjords, which is rapidly transformed or diluted as it enters the marine carbon cycle.
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The microbial diversity and metabolite production of the tropical ascidian Eudistoma vannamei reveals its role as a holobiont rich in secondary metabolites.
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SIRIUS compound classification reveals how maternal and environmental factors shape infant gut metabolism.
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Ash trees resistant to ash dieback could also help protect against emerald ash borer infestations.
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Females of the red-necked wasp moth have higher concentrations of potential defensive compounds than males.
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Key chemical cues for designing a biomaterial that mimics the chemical landscape of healthy reefs to enhance coral settlement.
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Metabolites altered up to 14 years before diagnosis enable the prediction of Crohn’s disease with high accuracy years before symptoms appear.
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Untargeted 2D chromtography MS/MS approach unravels the complex structures of depolymerized lignin to turn it into valuable biomaterials.
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Metabolites in maize grown on sustainable push-pull fields that enhance its natural defense against pests.
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Kakadu plum extracts shows antiproliferative effects against MCF7 breast adenocarcinoma cells.
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Selective cytotoxic activity of dinoflagellate Amphidinium eilatiense extracts against cancer cells is linked to a rich chemical diversity.
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Ketamine distribution in the brain improves understanding on how ketamine traverses the blood-brain barrier.
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Interplay between dietary patterns, plasma metabolites, and colorectal cancer risk
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18 novel hop-acid analogues identified in brewery waste revealing its high antioxidant potential.
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37 unique secondary metabolites identified in the metabolome of the invasive Guinea grass.
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Anti-viral compounds in Caesalpinia mimosoides help to inhibit influenza by targeting two critical viral proteins.
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Unstable metabolites in neonatal dried blood spot should be carefully monitored in long-term storage.
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Metabolites identified from A. absinthium extracts support the traditional use for stomach problems.
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Honey ia a bio-indicator for flame retardants in air.
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155 new brown carbon chromophores identified in aqueous-phase reactions of α-dicarbonyls with ammonium or amines.
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MCheM chemical labeling provides structural information to constrain the molecular structure search space in SIRIUS and boost annotation accuracy.
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Decoding the crucial role of the gut microbiome in altering the chemical structure and efficacy of GPCR drugs.
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Arctic microbes eat fresh plants instead of old soil—keeping ancient carbon safely stored.
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Antioxidant-rich extract from Ceratonia siliqua pods with potential for a biocompatible topical therapy.
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Environmental fate of formulation ingredients in commercial pesticides.
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Detailing the metabolic basis for the production of sesquiterpenoids in the medicinal mushroom Sanghuangporus.
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Innovative approach to prioritise chemical profiling over exhaustive identification for analysing and comparing biomes.
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Terpenoids might contribute to the success of M. calvescens as an invasive species.
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DX protein enhances expression of specialized metabolic pathways in the Streptomyces genomes and might lead to the discovery of novel bioactive molecules.
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Potential to enhance the skin health: changes in the skin metabolome more pronounced than in microbial composition.
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Stable isotope labeling serves as a detection strategy to distinguish biologically relevant features from background signals.
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Microbiome of eelgrass produces broad-spectrum antibiotics with potent activity against waterborne pathogens.
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False daisies contain anti-inflammatory, antioxidant and anti-collagenase ingredients with anti-aging potential .
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Previously undetected chemicals with potential estrogenic activity in drinking water from regions with high breast cancer incidence.
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Phosphorous limitation led to the creation of new types of lipids in Desulfatibacillum alkenivorans as survival strategy.
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Plants tailor their defenses based on the presence of herbivores rather than herbivore identity.
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Method to reveal the chemical potential of marine microorganisms based on microbial extracts.
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Microbial decomposition of human cadavers as data basis for a forensic tool to predict time since death.
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Highly halogenated compounds are potential contributors to the high antibacterial activity in tetrasporophyte stage of red alga Asparagopsis armata.
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Diurnal carbohydrate and metabolite production in sugarcane and energy-cane reveals differences in growth strategies.
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Identification of 100 light-absorbing brown carbon molecules, 33 of which have never been reported before.
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New degradation metabolites and potential metabolic pathway of novel designer drug O-PCE identified.
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Defense syndromes in willows result from a complex interplay of selection pressures and trade-offs.
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Green solvents can effectively extract diverse bioactive compounds from lemon balm leaves.
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33 emerging contaminants identified in global tap water — 25 for the first time.
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Tracing thousands of neuroactive metabolites from plant to pill: Vertigoheel retains characteristic constituents from its natural sources in all tested formulations.
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Potential new UV-protective amino acids identified in Baltic flatfish eyes.
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Metabolic adaptations of a salt-tolerant willow are specific to the plant organ and the salt anion.
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Multi-omic analysis reveals PHACTR1 as a master regulator of cell cycle, iron metabolism, and mitochondrial bioenergetics in human vascular cells.
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Unique phytochemical fingerprints of Phragmites australis lineages suggest that metabolomic evenness may be a critical trait within plant species.
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Testing different reversed-phase LC columns and mobile phase modifiers to improve coverage of intestinal lipids for non-targeted lipidomics.
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Understanding the dynamics of thawing permafrost and its impact on climate change is essential for developing strategies to cope with its effects.
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Nitrogen source drives Microcystis (a primary driver of harmful freshwater algal blooms) exometabolome composition more than strain, with nitrate fueling peak chemical diversity.
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Neuroprotective effects of secondary metabolites in mulberry plant extracts on Alzheimer’s Disease.
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Biopesticide 6-PP is produced via the polyketide biosynthesis pathway in Trichoderma fungi.
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Matrix Method: Streamlined, automated method using barcoded tubes to extract both DNA and metabolites simultaneously from human and environmental samples.
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Decreased concentration of two carotenoids after UV filter explosion might be indicative of an alteration in the photosynthetic capacity of corals.
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32-44% of polar chemicals in offshore oil discharges are persistent, in particular N-substituted aromatic ring structures.
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Ethanol extraction for human faecal metabolomics is a valid, safer, and more economical alternative to the common methanol extraction.
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New chlorophylls in coastal halophyte plant that exhibit potent, selective toxicity against colorectal cancer cells.
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Hybrid diversity in Baccharis is driven by secondary metabolites, while primary metabolism remains conserved.
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Chemical pollination syndrome: bird-syndrome nectar shows convergence on chemical traits distinct from bee-syndrome nectar.
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The methanogenic archaeon Methanosarcina barkeri can reduce naturally occurring iron oxides in aquatic sediments' methanogenic zones.
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Potent antidiabetic compounds in cluster fig (Ficus racemosa) fruit extracts.
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Cell surface glycans and membrane lipids are influential drivers of adaptation to heat stress in rice coral hosting thermosensitive and thermotolerant symbionts.
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Accelerated photoaging and contact with water significantly increase the degradation and transformation rates of rubber-derived chemicals.
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New protocol to identify structurally related impurities in pesticides for assessing their environmental impact and risks.
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Domesticated common bean varieties exhibit reduced metabolic diversity and specialization compared to their wild counterparts.
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Extremophilic fungi dissolve Martian-like hematite using a cocktail of siderophores and organic acids, creating stable chemical biosignatures detectable by future planetary missions.
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