Discoveries

See the impact of SIRIUS firsthand! This archive showcases exciting discoveries and major breakthroughs made by research groups worldwide. Explore how the power of SIRIUS is elevating small molecule data analysis across diverse fields, including drug discovery, human health, diagnostics, food industry, monitoring, microbiomics, environmental toxicology, and materials science. For an extensive list of publications by independent research groups using the SIRIUS software framework, click here.

Discoveries

It’s in your breath: pediatric asthma diagnosis using SIRIUS compound annotation

Pediatric asthma poses diagnostic challenges due to its variable presentation. Breath analysis could be a game-changer in pediatric allergic asthma management. By identifying unique exhaled metabolic signatures using SESI-MS and SIRIUS, this cutting-edge approach distinguishes children with allergic asthma from healthy controls, aiding accurate diagnosis and personalized treatment.

Franziska Hufsky 2023-05-26 No Comments

Discoveries

Long-term storage in biobanks: Identifying unstable metabolites with SIRIUS

Neonatal dried blood spots are not only important for newborn screening but also a powerful source for investigating the potential metabolic etiologies of various diseases using untargeted LC-MS-based metabolomics. So far it is unclear whether the metabolites in those samples remain stable in storage. SIRIUS helps to investigate the stability of metabolites and classes of molecules.

Franziska Hufsky 2023-05-11 No Comments