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SIRIUS is setting new standards in molecular identification, enabling the elucidation of previously uncharted compounds, and making a valuable contribution to both science and industry. Here you’ll find a variety of posts showcasing how SIRIUS advances metabolomics and molecular identification.

  • Discoveries: Explore how research groups are leveraging the power of SIRIUS to elevate their metabolomics data analysis across various fields, including drug discovery, diagnostics, food industry, environmental toxicology, and materials science. For an extensive list of discoveries, click here.
  • Application Notes: Learn practical strategies from our real-world applications alongside detailed information on how to get the most out of SIRIUS in your analyses.
  • Tutorials: Read our step-by-step guides to help you master SIRIUS features and workflows.
  • Projects: Our commitment is to continue improving SIRIUS and shaping the future of metabolomics research by initiating new research projects.
  • Background: Learn more about the science and concepts behind SIRIUS to get a deeper understanding of its capabilities.
Discoveries

Thawing permafrost: Another step towards assessing the consequences

Thawing permafrost, caused by climate change, releases stored carbon into the atmosphere, accelerating global warming. The enzyme latch hypothesis suggests that low-oxygen conditions in wetlands slow down enzymatic polyphenol degradation and carbon release. But are oxygen-dependent phenol oxidases really the only enzymes that microbial communities have in their arsenal? Or should we perhaps take a closer (metatranscriptomic and metabolomic) look at the microbially catalysed carbon cycle?

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Franziska Hufsky 2024-06-06 No Comments
Discoveries

The sky is burning: Elucidating brown carbon composition using CSI:FingerID

Brown carbon, arising from the combustion of organic matter, exerts a significant influence on atmospheric radiation and global climate. To fully comprehend its impact on atmospheric processes, a thorough characterization of the light-absorbing brown carbon molecules is imperative. Using CSI:FingerID, researchers have successfully annotated 100 brown carbon chromophores, 33 of which have never been reported before. Through the identification and characterization of these chromophores in diverse atmospheric samples, we gain invaluable insights into their origins, behavior, and the profound implications they have on radiative forcing, cloud formation, and the intricate web of global climate change.

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Franziska Hufsky 2023-07-05 No Comments