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SIRIUS is setting new standards in molecular identification, enabling the elucidation of previously uncharted compounds, and making a valuable contribution to both science and industry. Here you’ll find a variety of posts showcasing how SIRIUS advances metabolomics and molecular identification.

  • Discoveries: Explore how research groups are leveraging the power of SIRIUS to elevate their metabolomics data analysis across various fields, including drug discovery, diagnostics, food industry, environmental toxicology, and materials science. For an extensive list of discoveries, click here.
  • Application Notes: Learn practical strategies from our real-world applications alongside detailed information on how to get the most out of SIRIUS in your analyses.
  • Tutorials: Read our step-by-step guides to help you master SIRIUS features and workflows.
  • Projects: Our commitment is to continue improving SIRIUS and shaping the future of metabolomics research by initiating new research projects.
  • Background: Learn more about the science and concepts behind SIRIUS to get a deeper understanding of its capabilities.
Microbial breakdown, facilitated by microorganisms like bacteria and fungi, plays a pivotal role in decomposing organic matter. (Image by Thomas Breher on Pixabay)
Discoveries

SIRIUS on the body farm: Investigating microbial decomposers

Microbial decomposers break down human remains, recycling nutrients and influencing ecosystem dynamics. Is there a universal microbial decomposer network that assembles in response to mammalian remains? How does the network and the cadaver-derived nutrient pool change during the decomposition process and can this microbial community change be used for predicting time since death for forensic purposes?

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Franziska Hufsky 2024-02-23 No Comments
Current wastewater treatment plants often struggle to effectively remove antibiotics and their transformation products.
Discoveries

Biotransformation of antibiotics in wastewater: A fungal solution investigated with SIRIUS

Antibiotics are crucial for fighting bacterial infections, but the rise of antibiotic resistance poses a serious threat to public health. Beyond healthcare, the presence of antibiotic residues in wastewater exacerbates the problem. Conventional treatment methods often fall short in adequately removing these compounds, perpetuating resistance. Biological processes, such as biotransformation by fungi, have emerged as promising alternatives. Researchers investigated the potential of fungi to transform antibiotics, using SIRIUS and CSI:FingerID to identify degradation products.

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Franziska Hufsky 2024-02-09 1 Comment