A recent review on meta-analysis-ready evidence in exposomics analysis cites SIRIUS as an established, trusted infrastructure and go-to reference tools for structural and class-level annotation in the field.
SIRIUS is one of the mature, working pillars of the “annotation side” of the untargeted metabolomics/exposomics toolkit — evidence that annotation technology has “arrived”. But integration of such annotations across studies is the unsolved problem.
T. Hartung. Front. Artif. Intell. (2026) doi: 10.3389/frai.2026.1901969
