contaminants Archives - Bright Giant

SIRIUS is setting new standards in molecular identification, enabling the elucidation of previously uncharted compounds, and making a valuable contribution to both science and industry. Here you’ll find a variety of posts showcasing how SIRIUS advances metabolomics and molecular identification.

Discoveries: Explore how research groups are leveraging the power of SIRIUS to elevate their metabolomics data analysis across various fields, including drug discovery, diagnostics, food industry, environmental toxicology, and materials science. For an extensive list of discoveries, click here.
Application Notes: Learn practical strategies from our real-world applications alongside detailed information on how to get the most out of SIRIUS in your analyses.
Tutorials: Read our step-by-step guides to help you master SIRIUS features and workflows.
Projects: Our commitment is to continue improving SIRIUS and shaping the future of metabolomics research by initiating new research projects.
Background: Learn more about the science and concepts behind SIRIUS to get a deeper understanding of its capabilities.

Wooden pipe in the forest from which spring water flows

Application Notes

Detecting pharmaceuticals and their transformation products with SIRIUS

Pharmaceutical pollution poses risks to ecosystems and human health, yet traditional annotation methods often miss transformation products—drug breakdown compounds that may be even more persistent. We demonstrate how SIRIUS enhances annotation of pharmaceuticals in Luxembourgish rivers, from precursor drug screening to transformation product screening. Our approach for environmental monitoring is relevant not only for pharmaceuticals but also for pesticides and industrial chemicals, whose degradation products may have significant environmental impacts.

Franziska Hufsky 2025-04-28 No Comments

Assorted liquor bottles in a bar. Plastic-related contaminants in liquor products were even found in glass packaging.

Discoveries

Screening extractables and leachables with SIRIUS: Plastic-related contaminants in liquor products

In a world where we’re becoming increasingly conscious of what we consume, understanding the potential presence of unexpected extractables and leachables in our food and drinks is paramount. Alcoholic beverages are of particular concern due to their increased affinity and extended storage periods. A non-targeted approach to analysis is essential for uncovering both known and unknown contaminants in our drinks. By analysing fragmentation patterns, SIRIUS predicts chemical structures of unknowns to identify unexpected contaminants and ensure safety of our food.

Franziska Hufsky 2024-09-30 No Comments