SIRIUS 5 | End of life

SIRIUS 5 | End of life

Important Announcement for SIRIUS 5 Users: Please be aware that maintenance and support for SIRIUS 5 will officially end on February 28, 2026.

To ensure you continue to benefit from the latest advancements in small molecule identification from mass spectrometry data, we highly recommend upgrading to SIRIUS 6.

The easy way to comprehensive structure elucidation​

SIRIUS is the comprehensive software solution for the high-throughput identification of small molecules from fragmentation mass spectrometry data. SIRIUS provides a comprehensive set of features spanning every step from feature detection to detailed result validation. It is designed to not only accurately characterize known compounds but also to confidently identify “unknown unknowns” in complex biological samples. 

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