Discoveries

• 37 unique secondary metabolites identified in the metabolome of the invasive Guinea grass.
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• 48 antioxidation active metabolites identified in Ginger.
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• 155 new brown carbon chromophores identified in aqueous-phase reactions of α-dicarbonyls with ammonium or amines.
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• Antioxidant-rich extract from Ceratonia siliqua pods with potential for a biocompatible topical therapy.
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• Ash trees resistant to ash dieback could also help protect against emerald ash borer infestations.
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• Biochemical pathways and compounds of the unique stress response of liverworts with potential cytotoxicity against human cancer cell lines.
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• Biotransformation of levofloxacin in wastewater by basidiomycete fungal strains leads to decreased antibiotic activity.
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• Chemical composition and anti-inflammatory properties of prickly goldenfleece could be a valuable source of bioactive compounds for food and health applications.
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• Cortisol, sumatriptan, and glutamine are crucial metabolites associated with the treatment of migraines with triptans.
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• Decreased concentration of two carotenoids after UV filter explosion might be indicative of an alteration in the photosynthetic capacity of corals.
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• Defense syndromes in willows result from a complex interplay of selection pressures and trade-offs.
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• Different paths to chemical diversity in highland and lowland willow species.
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• Diurnal carbohydrate and metabolite production in sugarcane and energy-cane reveals differences in growth strategies.
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• Domesticated common bean varieties exhibit reduced metabolic diversity and specialization compared to their wild counterparts.
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• DX protein enhances expression of specialized metabolic pathways in the Streptomyces genomes and might lead to the discovery of novel bioactive molecules.
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• Endophytic bacteria aid in controlling fusarium wilt disease and enhancing tomato plant growth through bioactive secondary metabolites.
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• Environmental fate of formulation ingredients in commercial pesticides.
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• False daisies contain anti-inflammatory, antioxidant and anti-collagenase ingredients with anti-aging potential .
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• FODMAPs are influencing health-positive metabolites in plasma of irritable bowel syndrome patients.
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• Grapevine root extracts rich in oligostilbenes show high antifungal activity against fungal plant pathogen that affects cereal crops.
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• Highly halogenated compounds are potential contributors to the high antibacterial activity in tetrasporophyte stage of red alga Asparagopsis armata.
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• Honey ia a bio-indicator for flame retardants in air.
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• Identification of 100 light-absorbing brown carbon molecules, 33 of which have never been reported before.
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• Identify and link microbial metabolites to their producers with microbeMASST and SIRIUS.
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• Interplay between dietary patterns, plasma metabolites, and colorectal cancer risk
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• Kakadu plum extracts shows antiproliferative effects against MCF7 breast adenocarcinoma cells.
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• Ketamine distribution in the brain improves understanding on how ketamine traverses the blood-brain barrier.
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• Marine prokaryotes hold vast potential for discovering new drug candidates.
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• Metabolite from actinobacteria strain from Egyptian soil is a promising candidate as a multidrug efflux pump inhibitor.
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• Metabolite linked to dual-species biofilm pathogenesis in cystic fibrosis identified.
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• Metabolites from citrus juices improve herbal therapy against paracetamol-induced liver toxicity.
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• Metabolites identified from A. absinthium extracts support the traditional use for stomach problems.
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• Metabolites in maize grown on sustainable push-pull fields that enhance its natural defense against pests.
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• Metabolites of Aspergillus niveus are promising leads for developing new potent cholinesterase inhibitors against Alzheimer's disease.
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• Metabolome composition of mature and immature seeds from different cereal and leguminous plants.
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• Metabolomic profiles of three Ficus species to investigate phytochemistry, chemotaxonomy and potential medical use.
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• Metabolomics study of black apples revealed the chemical diversity of fungus-produced secondary metabolites in black apple microbiomes.
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• Method to reveal the chemical potential of marine microorganisms based on microbial extracts​​.
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• Microbial biocontrol agents lead to major metabolic re-programming in fungi
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• Microbial decomposition of human cadavers as data basis for a forensic tool to predict time since death.
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• Microbiome of eelgrass produces broad-spectrum antibiotics with potent activity against waterborne pathogens.
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• Molecular explanation for the longer time needed to establish the low-compatibility interaction between the ectomycorrhizal fungus Tricholoma vaccinum and pine.
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• Neuroprotective effects of secondary metabolites in mulberry plant extracts on Alzheimer’s Disease.
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• New degradation metabolites and potential metabolic pathway of novel designer drug O-PCE identified.
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• New ecdysteroids with potential skin aging therapeutic benefits discovered in the Korean plant Ajuga spectabilis.
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• New protocol to identify structurally related impurities in pesticides for assessing their environmental impact and risks.
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• Non-targeted approach uncovers plastic-related contaminants in liquor products, including three unanticipated compounds.
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• Novel method to study ozonation in water treatment plants to remove cyanobacterial toxins from drinking water.
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• Nutritional components of coconut flesh.
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• Oscillibacter species in the gut microbiome may help lower cholesterol levels, potentially benefiting heart health.
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• Phosphorous limitation led to the creation of new types of lipids in Desulfatibacillum alkenivorans as survival strategy.
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• Plant extracts as reducing agents for the environmentally friendly synthesis of silver nanoparticles.
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• Plants tailor their defenses based on the presence of herbivores rather than herbivore identity.
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• Potential to enhance the skin health: changes in the skin metabolome more pronounced than in microbial composition.
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• Significant differences in metabolite abundance and composition among microalgae Spirulina, Chlorella, and Amphora.
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• Specific metabolites identified as potential selection traits to improve Fusarium resistance in maize.
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• Stable isotope labeling serves as a detection strategy to distinguish biologically relevant features from background signals.
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• Terpenoids might contribute to the success of M. calvescens as an invasive species.
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• Testing different reversed-phase LC columns and mobile phase modifiers to improve coverage of intestinal lipids for non-targeted lipidomics.
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• The methanogenic archaeon Methanosarcina barkeri can reduce naturally occurring iron oxides in aquatic sediments' methanogenic zones.
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• The microbial diversity and metabolite production of the tropical ascidian Eudistoma vannamei reveals its role as a holobiont rich in secondary metabolites.
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• Understanding the dynamics of thawing permafrost and its impact on climate change is essential for developing strategies to cope with its effects.
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• Unique phytochemical fingerprints of Phragmites australis lineages suggest that metabolomic evenness may be a critical trait within plant species.
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• Unstable metabolites in neonatal dried blood spot should be carefully monitored in long-term storage.
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• Untargeted 2D chromtography MS/MS approach unravels the complex structures of depolymerized lignin to turn it into valuable biomaterials.
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• White adipose tissue plays a crucial role in regulating metabolism throughout the hibernation cycle.
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• Zinc anodes, used to protect against corrosion in marine environments, affect the metabolism of oysters.
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