Discoveries

• 18 novel hop-acid analogues identified in brewery waste revealing its high antioxidant potential.
  Loading...
  new
• 32-44% of polar chemicals in offshore oil discharges are persistent, in particular N-substituted aromatic ring structures.
  Loading...
  new
• 33 emerging contaminants identified in global tap water — 25 for the first time.
  Loading...
  new
• 37 unique secondary metabolites identified in the metabolome of the invasive Guinea grass.
  Loading...
• 48 antioxidation active metabolites identified in Ginger.
  Loading...
• 155 new brown carbon chromophores identified in aqueous-phase reactions of α-dicarbonyls with ammonium or amines.
  Loading...
• Accelerated photoaging and contact with water significantly increase the degradation and transformation rates of rubber-derived chemicals.
  Loading...
  new
• Annotating nitazine (high-potency synthetic opioid) metabolites and major markers for enhanced detection.
  Loading...
• Annotation of 80% of the previously unknown metabolite features of tall wheatgrass root exudates.
  Loading...
• Anti-viral compounds in Caesalpinia mimosoides help to inhibit influenza by targeting two critical viral proteins.
  Loading...
• Antioxidant-rich extract from Ceratonia siliqua pods with potential for a biocompatible topical therapy.
  Loading...
• Arctic microbes eat fresh plants instead of old soil—keeping ancient carbon safely stored.
  Loading...
  new
• Ash trees resistant to ash dieback could also help protect against emerald ash borer infestations.
  Loading...
• Biochemical pathways and compounds of the unique stress response of liverworts with potential cytotoxicity against human cancer cell lines.
  Loading...
• Biopesticide 6-PP is produced via the polyketide biosynthesis pathway in Trichoderma fungi.
  Loading...
• Biotransformation of levofloxacin in wastewater by basidiomycete fungal strains leads to decreased antibiotic activity.
  Loading...
• Blechnic acid B: novel lignan discovered in ferns of the Blechnaceae family.
  Loading...
  new
• Brazilian iron-cave bacteria produce rare cyclopeptides with significant cytotoxic activity against cancer cells.
  Loading...
  new
• Cell surface glycans and membrane lipids are influential drivers of adaptation to heat stress in rice coral hosting thermosensitive and thermotolerant symbionts.
  Loading...
• Chemical composition and anti-inflammatory properties of prickly goldenfleece could be a valuable source of bioactive compounds for food and health applications.
  Loading...
• Chemical pollination syndrome: bird-syndrome nectar shows convergence on chemical traits distinct from bee-syndrome nectar.
  Loading...
  new
• Climate and island residence time influence plant specialised chemical diversity.
  Loading...
  new
• Common and previously unreported parabens and plastic-related contaminants identified in human milk.
  Loading...
• Cortisol, sumatriptan, and glutamine are crucial metabolites associated with the treatment of migraines with triptans.
  Loading...
• Decoding the crucial role of the gut microbiome in altering the chemical structure and efficacy of GPCR drugs.
  Loading...
• Decreased concentration of two carotenoids after UV filter explosion might be indicative of an alteration in the photosynthetic capacity of corals.
  Loading...
• Deep-sea black yeasts adapt to extreme salinity by remodeling membranes and accumulating plant-like amino acids and novel aminocyclitols to maintain osmotic balance.
  Loading...
  new
• Defense syndromes in willows result from a complex interplay of selection pressures and trade-offs.
  Loading...
• Detailing the metabolic basis for the production of sesquiterpenoids in the medicinal mushroom Sanghuangporus.
  Loading...
• Different paths to chemical diversity in highland and lowland willow species.
  Loading...
• Diurnal carbohydrate and metabolite production in sugarcane and energy-cane reveals differences in growth strategies.
  Loading...
• Domesticated common bean varieties exhibit reduced metabolic diversity and specialization compared to their wild counterparts.
  Loading...
• Drug metabolites and drugrelated impurities in human plasma identified without reference standards and a priori knowledge of first- and second-pass drug metabolism.
  Loading...
  new
• DX protein enhances expression of specialized metabolic pathways in the Streptomyces genomes and might lead to the discovery of novel bioactive molecules.
  Loading...
• Eccrine finger sweat analysis reveals healthy lifestyle shifts in children with overweight after long-term nutritional education and lifestyle intervention.
  Loading...
  new
• Endophytic bacteria aid in controlling fusarium wilt disease and enhancing tomato plant growth through bioactive secondary metabolites.
  Loading...
• Environmental fate of formulation ingredients in commercial pesticides.
  Loading...
• Ethanol extraction for human faecal metabolomics is a valid, safer, and more economical alternative to the common methanol extraction.
  Loading...
• Extremophilic fungi dissolve Martian-like hematite using a cocktail of siderophores and organic acids, creating stable chemical biosignatures detectable by future planetary missions.
  Loading...
  new
• False daisies contain anti-inflammatory, antioxidant and anti-collagenase ingredients with anti-aging potential .
  Loading...
• Females of the red-necked wasp moth have higher concentrations of potential defensive compounds than males.
  Loading...
• FODMAPs are influencing health-positive metabolites in plasma of irritable bowel syndrome patients.
  Loading...
• Glacial rivers deliver highly bioavailable aliphatic matter to Arctic fjords, which is rapidly transformed or diluted as it enters the marine carbon cycle.
  Loading...
  new
• Grapevine root extracts rich in oligostilbenes show high antifungal activity against fungal plant pathogen that affects cereal crops.
  Loading...
• Green solvents can effectively extract diverse bioactive compounds from lemon balm leaves.
  Loading...
• Highly halogenated compounds are potential contributors to the high antibacterial activity in tetrasporophyte stage of red alga Asparagopsis armata.
  Loading...
• Highly specific "Gold" markers in 14 yellow dye plants enable the precise botanical authentication of ancient textiles.
  Loading...
  new
• Homologous series of previously overlooked polymerization byproducts detected near fluoropolymer production plant.
  Loading...
• Honey ia a bio-indicator for flame retardants in air.
  Loading...
• Hybrid diversity in Baccharis is driven by secondary metabolites, while primary metabolism remains conserved.
  Loading...
  new
• Identification of 100 light-absorbing brown carbon molecules, 33 of which have never been reported before.
  Loading...
• Identification of fenozan in wastewater as a key biomarker for human exposure to synthetic phenolic antioxidants.
  Loading...
  new
• Identify and link microbial metabolites to their producers with microbeMASST and SIRIUS.
  Loading...
• Increase in released greenhouse gases in Northern peatlands is likely due to changes in metabolic activity rather than microbial community changes.
  Loading...
  new
• Innovative approach to prioritise chemical profiling over exhaustive identification for analysing and comparing biomes.
  Loading...
• In ruminants, rutin is first degraded to quercetin by rumen microbes, which is then biotransformed into various phenolic compounds that ultimately result in 4-methylcatechol-1-sulfate and isorhamnetin-glucuronide sulfate as the main metabolites found in the blood
  Loading...
• Interplay between dietary patterns, plasma metabolites, and colorectal cancer risk
  Loading...
• Kakadu plum extracts shows antiproliferative effects against MCF7 breast adenocarcinoma cells.
  Loading...
• Ketamine distribution in the brain improves understanding on how ketamine traverses the blood-brain barrier.
  Loading...
• Key chemical cues for designing a biomaterial that mimics the chemical landscape of healthy reefs to enhance coral settlement.
  Loading...
  new
• Link between microbial community structure and chemical profile of the surface metabolome in Saccharina latissima.
  Loading...
• Lipophilic diterpenoids and retinoids in seaweed reduce rumen methane production by 30% while shifting fermentation patterns.
  Loading...
  new
• Major antihypertensive constituents of Kinkéliba decoction confirmed through high-resolution metabolite annotation.
  Loading...
  new
• Marine prokaryotes hold vast potential for discovering new drug candidates.
  Loading...
• Matrix Method: Streamlined, automated method using barcoded tubes to extract both DNA and metabolites simultaneously from human and environmental samples.
  Loading...
  new
• MCheM chemical labeling provides structural information to constrain the molecular structure search space in SIRIUS and boost annotation accuracy.
  Loading...
• Metabolic adaptations of a salt-tolerant willow are specific to the plant organ and the salt anion.
  Loading...
• Metabolite from actinobacteria strain from Egyptian soil is a promising candidate as a multidrug efflux pump inhibitor.
  Loading...
• Metabolite linked to dual-species biofilm pathogenesis in cystic fibrosis identified.
  Loading...
• Metabolites altered up to 14 years before diagnosis enable the prediction of Crohn’s disease with high accuracy years before symptoms appear.
  Loading...
  new
• Metabolites from citrus juices improve herbal therapy against paracetamol-induced liver toxicity.
  Loading...
• Metabolites identified from A. absinthium extracts support the traditional use for stomach problems.
  Loading...
• Metabolites in maize grown on sustainable push-pull fields that enhance its natural defense against pests.
  Loading...
• Metabolites of Aspergillus niveus are promising leads for developing new potent cholinesterase inhibitors against Alzheimer's disease.
  Loading...
• Metabolome composition of mature and immature seeds from different cereal and leguminous plants.
  Loading...
• Metabolomic profiles of three Ficus species to investigate phytochemistry, chemotaxonomy and potential medical use.
  Loading...
• Metabolomics study of black apples revealed the chemical diversity of fungus-produced secondary metabolites in black apple microbiomes.
  Loading...
• Method to reveal the chemical potential of marine microorganisms based on microbial extracts​​.
  Loading...
• Microbial biocontrol agents lead to major metabolic re-programming in fungi
  Loading...
• Microbial decomposition of human cadavers as data basis for a forensic tool to predict time since death.
  Loading...
• Microbiome of eelgrass produces broad-spectrum antibiotics with potent activity against waterborne pathogens.
  Loading...
• Microtiter plate cultivation systems provide a robust platform for discovering novel bacterial natural products by enabling broader access to chemical diversity.
  Loading...
• Molecular explanation for the longer time needed to establish the low-compatibility interaction between the ectomycorrhizal fungus Tricholoma vaccinum and pine.
  Loading...
• Monophasic extraction with 400 nm beads and 60-minute on-bead protein digestion is the most reproducible, efficient, and cost-effective solution for in-house multiomics (metabolites, lipids, proteins) workflows in HepG2 cells.
  Loading...
  new
• Multi-omic analysis reveals PHACTR1 as a master regulator of cell cycle, iron metabolism, and mitochondrial bioenergetics in human vascular cells.
  Loading...
  new
• Multi-omics reveals coating-specific signatures—like ceramides and glucosinolates—that govern biofilm resilience.
  Loading...
  new
• Multidimensional optimization of cell morphology increases the reproducibility of microbial metabolic footprints by 50% across different cultivation systems.
  Loading...
  new
• Mycobacteria use the MelH protein to neutralize toxic lipids, allowing them to survive in the host.
  Loading...
  new
• Mycobacteria use the MelH protein to neutralize toxic lipids, allowing them to survive in the host.
  Loading...
  new
• Neuroprotective effects of secondary metabolites in mulberry plant extracts on Alzheimer’s Disease.
  Loading...
• New chlorophylls in coastal halophyte plant that exhibit potent, selective toxicity against colorectal cancer cells.
  Loading...
  new
• New degradation metabolites and potential metabolic pathway of novel designer drug O-PCE identified.
  Loading...
• New ecdysteroids with potential skin aging therapeutic benefits discovered in the Korean plant Ajuga spectabilis.
  Loading...
• New protocol to identify structurally related impurities in pesticides for assessing their environmental impact and risks.
  Loading...
• Nitrogen source drives Microcystis (a primary driver of harmful freshwater algal blooms) exometabolome composition more than strain, with nitrate fueling peak chemical diversity.
  Loading...
  new
• Non-targeted approach uncovers plastic-related contaminants in liquor products, including three unanticipated compounds.
  Loading...
• Novel method to study ozonation in water treatment plants to remove cyanobacterial toxins from drinking water.
  Loading...
• Novel urinary biomarkers to distinguish giant panda pregnancy from pseudopregnancy as early as the first weeks of embryonic development.
  Loading...
  new
• Nutritional components of coconut flesh.
  Loading...
• Oscillibacter species in the gut microbiome may help lower cholesterol levels, potentially benefiting heart health.
  Loading...
• Phosphorous limitation led to the creation of new types of lipids in Desulfatibacillum alkenivorans as survival strategy.
  Loading...
• Plant extracts as reducing agents for the environmentally friendly synthesis of silver nanoparticles.
  Loading...
• Plants tailor their defenses based on the presence of herbivores rather than herbivore identity.
  Loading...
• Potent antidiabetic compounds in cluster fig (Ficus racemosa) fruit extracts.
  Loading...
  new
• Potentially allergenic transformation products of tattoo pigments identified in new online-LC-EC-MS approach.
  Loading...
• Potential new UV-protective amino acids identified in Baltic flatfish eyes.
  Loading...
  new
• Potential to enhance the skin health: changes in the skin metabolome more pronounced than in microbial composition.
  Loading...
• Previously overlooked toxic drivers identified in the air, including 2-indanone and 2-vinylpyridine.
  Loading...
  new
• Previously undetected chemicals with potential estrogenic activity in drinking water from regions with high breast cancer incidence.
  Loading...
• Robust biomarker candidate identified for standardizing exhaled breath sample collection.
  Loading...
  new
• Rust infection in common beans enriched metabolomic pathways, biosynthesis of secondary metabolites, protein processing in the endoplasmic reticulum, and purine metabolism among others.
  Loading...
• Selective cytotoxic activity of dinoflagellate Amphidinium eilatiense extracts against cancer cells is linked to a rich chemical diversity.
  Loading...
• Significant differences in metabolite abundance and composition among microalgae Spirulina, Chlorella, and Amphora.
  Loading...
• SIRIUS as part of a new screening platform to efficiently discover antifungal drugs from natural sources.
  Loading...
• SIRIUS compound classification reveals how maternal and environmental factors shape infant gut metabolism.
  Loading...
  new
• SIRIUS tentatively identified dadahol A in hemp roots, guiding the discovery of neolignans with cytotoxic activity against pediatric cancer cells.
  Loading...
  new
• Specific metabolites identified as potential selection traits to improve Fusarium resistance in maize.
  Loading...
• Stable isotope labeling serves as a detection strategy to distinguish biologically relevant features from background signals.
  Loading...
• Strong interdependence and metabolic rewiring of the algal partner in radiolaria photosymbiosis, where the host extensively transforms algal metabolites and the algal cell membrane is significantly rearranged.
  Loading...
• Terpenoids might contribute to the success of M. calvescens as an invasive species.
  Loading...
• Testing different reversed-phase LC columns and mobile phase modifiers to improve coverage of intestinal lipids for non-targeted lipidomics.
  Loading...
• The antimicrobial agent trimethoprim influences chemical interactions between cystic fibrosis pathogens affecting virulence factors.
  Loading...
• The International Space Station has a unique and extreme microbial and chemical environment with distinct signatures within each module.
  Loading...
• The methanogenic archaeon Methanosarcina barkeri can reduce naturally occurring iron oxides in aquatic sediments' methanogenic zones.
  Loading...
• The microbial diversity and metabolite production of the tropical ascidian Eudistoma vannamei reveals its role as a holobiont rich in secondary metabolites.
  Loading...
• Tracing thousands of neuroactive metabolites from plant to pill: Vertigoheel retains characteristic constituents from its natural sources in all tested formulations.
  Loading...
  new
• Understanding the dynamics of thawing permafrost and its impact on climate change is essential for developing strategies to cope with its effects.
  Loading...
• Unique phytochemical fingerprints of Phragmites australis lineages suggest that metabolomic evenness may be a critical trait within plant species.
  Loading...
• Unstable metabolites in neonatal dried blood spot should be carefully monitored in long-term storage.
  Loading...
• Untargeted 2D chromtography MS/MS approach unravels the complex structures of depolymerized lignin to turn it into valuable biomaterials.
  Loading...
• Upcycling by-products: Coffee waste is a rich source of hydrophilic antioxidants and lipophilic sterols.
  Loading...
  new
• White adipose tissue plays a crucial role in regulating metabolism throughout the hibernation cycle.
  Loading...
• Women with ovarian malignancies had significantly higher urinary levels of endocrine-disrupting chemicals.
  Loading...
• Zinc anodes, used to protect against corrosion in marine environments, affect the metabolism of oysters.
  Loading...